Abstract: 8.40 Retrospective Data Analysis In Breast Cancer Patients After Skin-Sparing Or Nipple-Sparing Mastectomy Prove Efficiency And Sustainability Of This Breastconserving Therapy
نویسندگان
چکیده
INtroductIoN: Treatment goal in cutaneous squamous cell carcinoma (SCC) is complete removal of the tumor with clear histological margins. Gold nanoparticles (GNPs) can be distributed to a tumor by conjugating them with an antibody specific to the tumor’s surface receptor. The consequent change in the optical properties of the cancerous tissue distinguishes it from normal tissue. Given that about 90% of SCCs overexpress epithelium-derived growth factor (EGFR), we sought to determine the sensitivity of diffusion reflection spectroscopy measurements of SCC targeted by GNPs bio-conjugated to anti-EGFR antibodies in identifying residual tumor in excision borders.
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Favorable Outcome with Close Margins in Patients Undergoing Nipple/Skin Sparing Mastectomy with Immediate Breast Reconstruction: 5-year Follow-up
BACKGROUND Implant-based breast reconstruction after mastectomy has recently been reported to be the preferred type of surgery among breast-specific surgeons and plastic surgeons. AIMS To explore the significant clinicopathological factors associated with long-term outcome related to local recurrences of the nipple among patients who underwent immediate breast reconstruction with tissue expan...
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متن کاملOptimizing the total skin-sparing mastectomy.
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BACKGROUND To address those patients who do not meet anatomical criteria for nipple-sparing mastectomy, the authors use a staged approach: (1) mastopexy or breast reduction, (2) nipple-sparing mastectomy through the mastopexy incisions after a minimum of 3 to 4 weeks, and (3) the final reconstruction. METHODS Fifteen patients underwent nipple-sparing mastectomy at Georgetown University Hospit...
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Background. Most women with breast cancer today can be managed with breast conservation; however, some women still require mastectomy for treatment of their disease. Skin-sparing mastectomy (SSM) with immediate reconstruction has emerged as a favorable option for many of these patients. The authors combined the SSM technique with the preservation of a small part of the areola with immediate nip...
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